Lesion load can be misleading if analysed globally. Once you begin looking at specific fiber pathways, details and specific effects can be extracted.
To do so, lesion localization is used to assess which fiber bundles are affected.
White matter integrity is specifically analyzed inside MS lesions and outside, in normal appearing white matter, to enable better patients selection in clinical trials.
Imeka’s tools can also track through lesions, to provide a better understanding of the underlying phenomena.