From Imeka and its collaborators
A. Pichet Binette, G. Theaud, F. Rheault, M. Roy, D L. Collins, J. Levin, H. Mori, J. Hong Lee, M. Rhys Farlow, P. Schofield, J. P. Chhatwal, C. L. Masters, T. Benzinger, J. Morris, R. Bateman, J. Cs Breitner, J. Poirier, J. Gonneaud, M. Descoteaux, S. Villeneuve, DIAN Study Group and the PREVENT-AD Research Group. Bundle-specific associations between white matter microstructure and Aβ and tau pathology in preclinical Alzheimer’s disease. Elife, May 13 2021.
M. Roy, F. Rheault, E. Croteau, C-A. Castellano, M. Fortier, V. St-Pierre, J-C. Houde, É. E. Turcotte, C. Bocti, T. Fulop, S. C. Cunnane, M. Descoteaux. Fascicle- and Glucose-Specific Deterioration in White Matter Energy Supply in Alzheimer’s Disease. Journal of Alzheimer Disease, June 15 2020
Geneviève Nolze-Charron, Raphaël Dufort-Rouleau, Jean-Christophe Houde, Matthieu Dumont, Christian-Alexandre Castellano, Stephen Cunnane, Dominique Lorrain, Tamàs Fülöp, Maxime Descoteaux, Christian Bocti. Tractography of the external capsule and cognition: A diffusion MRI study of cholinergic fibers, Experimental Gerontology, Volume 130, February 2020.
Dumont, M., M. Roy, P-M. Jodoin, F.C. Morency, J-C. Houde, Z. Xie, C. Bauer, T.A. Samad, K. R. A. Van Dijk, J. Goodman, M. Descoteaux, “Free water in white matter differentiates MCI and AD from control subjects”, Frontiers Aging Neuroscience, 02 October 2019.
M. Fortier, C.-a. Castellano, E. Croteau, F. Langlois, C. Bocti, V. St-pierre, C. Vandenberghe, M. Bernier, M. Roy, K. Whittingstall, M. Lepage, E. Turcotte, T. Fulop, and S. Cunnane. “A ketogenic drink improves brain energy and some measures of cognition in MCI.”, Alzheimer’s & Dementia, May, Volume 15, Issue 5, Pages 625–634, 2019
Other publications of interest
Fang Ji, Ofer Pasternak, Siwei Liu, Yng Miin Loke, Boon Linn Choo, Saima Hilal, Xin Xu, Mohammad Kamran Ikram, Narayanaswamy Venketasubramanian, Christopher Li-Hsian Chen & Juan Zhou, Distinct white matter microstructural abnormalities and extracellular water increases relate to cognitive impairment in Alzheimer’s disease with and without cerebrovascular disease, Alzheimer’s Research & Therapy, volume 9, 63. 2017.
Our webinars about research on Alzheimer
Maggie Roy, Ph.D. Research Center on Aging, SCIL.
The role of White Matter in Alzheimer’s Disease: New insights from Tractography and PET imaging.
Alexa Pichet Binette, Ph.D., postdoctoral fellow at Lund University, Sweden.
White matter microstructure and Alzheimer’s disease pathology: Insights from tractography and PET imaging
Maxime Descoteaux Ph.D. Imeka’s co-founder and CSO.
Diffusion MRI to map white matter integrity and assess neuroinflammation, demyelination and axonal loss.